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B12 shots are administered either intramuscularly (into the muscle) or subcutaneously (just under the skin)

10.1186/s12943-020-01258-7 Summary Keywords ulcerative colitis, GHK-Cu, SIRT1/STAT3 pathway, co-culture system, network pharmacology, molecular docking Citation Mao S, Huang J, Li J, Sun F, Zhang Q, Cheng Q, Zeng W, Lei D, Wang S and Yao J (2025) Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms

But it can also change blood flow and pressure

Measurements included hydrodynamic diameter (2RH), polydispersity index (PDI) and zeta potential (ZP) (Table 1), which were obtained using dynamic light scattering (DLS) with a NanoBrook Omni analyzer (Brookhaven Instruments Corporation, Holtsville, NY, USA)